Increased expression of miR142 and miR155 in glial and immune cells after traumatic brain injury may contribute to neuroinflammation via astrocyte activation
نویسندگان
چکیده
منابع مشابه
increased expression of glial cell line-derived neurotrophic factor in rat brain after traumatic brain injury
glial cell line-derived neurotrophic factor (gdnf) plays important roles not only for the differentiation of neurons during normal development but also for the survival and recovery of many populations of mature neurons. the effect of traumatic brain injury (tbi) on the expression of gdnf is currently unknown. to determine if there is alteration in gdnf after tbi we examined the effect of contr...
متن کاملIncreased Expression of Glial Cell Line-derived Neurotrophic Factor in Rat Brain after Traumatic Brain Injury
Glial cell line-derived neurotrophic factor (GDNF) plays important roles not only for the differentiation of neurons during normal development but also for the survival and recovery of many populations of mature neurons. The effect of traumatic brain injury (TBI) on the expression of GDNF is currently unknown. To determine if there is alteration in GDNF after TBI we examined the effect of contr...
متن کاملP 104: Effects of Human Neural Stem Cells in Cure Neuroinflammation of Traumatic Brain Injury
Traumatic brain injury (TBI) is defined as an external mechanical injury to the brain. Neuroinflammation plays a vital role in the pathophysiology of TBI. Microglia and astrocytes play a central role in the initiation and regulation of inflammation. Numerous pro-inflammatory mediators including cytokines, chemokines, reactive oxygen species (ROS) and nitric oxide (NO) released by microglia. In ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Brain Pathology
سال: 2020
ISSN: 1015-6305,1750-3639
DOI: 10.1111/bpa.12865